Multimodal Imaging Assessment After Revascularization in Patients With Acute Myocardial Infarction

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This prospective cohort study will enroll 20 patients clinically diagnosed with first-time acute myocardial infarction (AMI) who underwent interventional procedures (including percutaneous coronary intervention \[PCI\] and balloon angioplasty) at the Affiliated Hospital of Qingdao University. Patient data, including routine blood and urine tests, blood biochemistry, electrocardiograms (ECG), imaging studies, and interventional procedure records, will be collected to assess eligibility for enrollment. The study procedures include patient screening and enrollment, obtaining informed consent, baseline assessment (including medical history, laboratory tests, ECG, etc.), an ¹⁸F-Pentixafor PET/MR examination, and follow-up. Images will be blindly assessed by at least two specialized physicians from the Radiology and Nuclear Medicine departments. The study aims to investigate the utility of ¹⁸F-Pentixafor PET/MR in evaluating coronary microcirculatory function, cardiac function, myocardial viability, myocardial inflammatory response, and the efficacy of interventional therapy in AMI patients post-procedure. Additionally, it will perform risk stratification and prognostic analysis for the enrolled patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Patients with a clinical diagnosis of first-episode acute myocardial infarction (AMI) who underwent emergency percutaneous coronary intervention (PCI) were included. All patients had complete baseline clinical data, with baseline cardiac magnetic resonance (CMR) examinations performed within 7 days post-PCI and follow-up CMR completed at 6 months post-procedure.

Locations
Other Locations
China
The Affiliated Hospital of Qingdao University
RECRUITING
Qingdao
Contact Information
Primary
Pei Nie, MD
niepei@qdu.edu.cn
0532-82911500
Time Frame
Start Date: 2025-08
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 20
Treatments
clinically diagnosed with first-episode AMI and undergoing interventional therapy
Sponsors
Leads: The Affiliated Hospital of Qingdao University

This content was sourced from clinicaltrials.gov